动脉粥样硬化的早期病变主要侵犯血管壁而较少累及管腔。现行的以X线为代表的所有影像学诊断检查,都要在血管腔狭窄达到一定程度时,才能发现形态学的影像改变。此时病变发展往往已处于临床晚期阶段,血流动力学明显受损,病变几乎不可逆转。所以,现行的依赖于血管壁组织结构异常而进行诊断的所有影像学检查,对发现早期以代谢紊乱为特征的动脉粥样硬化,存在固有的局限性,且X线血管造影价格昂贵,对病人有创伤和一定危险性,不适于治疗病人的疗效观察和随访。针对该病发展具有隐匿性、慢性、进行性的特点,寻找新的检查手段,以便在病变发展可以逆转和恢复的早期进行 Early lesions of atherosclerosis predominantly encroach on the vessel wall with less involvement of the lumen. The current X-ray imaging diagnosis, represented by all, must be in the vascular stenosis to a certain extent, to find the morphological changes in the image. At this point the development of the disease is often already in the late stages of clinical, hemodynamic significantly damaged lesions almost irreversible. Therefore, all current imaging studies that depend on the abnormalities of the vascular wall tissue structure have inherent limitations in the detection of atherosclerosis characterized by metabolic disorders in the early stages, and that X-ray angiography is expensive, Trauma and a certain risk, not suitable for treatment of patients efficacy and follow-up. For the development of the disease with occult, chronic, progressive features, looking for new means of examination in order to reverse the development of lesions and early recovery