硫酸去氢表雄酮(DHAS)是肾上腺皮质分泌的激素。对妊娠末期的大白鼠,jv化学合成的DHAS一次,剂量分别为8和16mg/kg,大白鼠在给药后2h即可见子宫颈软化,20h后效果更显著。家兔在妊娠d21～d25给药,剂量分别为10和20mg/(kg·d),子宫颈明显软化,湿重显著增加。组织学检查,子宫颈呈明显水肿及充血。 Dehydroepiandrosterone sulfate (DHAS) is a hormone secreted by the adrenal cortex. For late gestation rats, jv chemical synthesis of DHAS once, the dose was 8 and 16mg / kg, 2h after administration of rats can be seen cervix softening, the effect is more significant after 20h. The rabbits were administered d21 ~ d25 in pregnancy at doses of 10 and 20 mg / (kg · d) respectively. The cervix softened significantly and the wet weight increased significantly. Histological examination, the cervix was significantly edema and congestion.