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作者对7例慢性阻塞性肝病患儿从临床、实验室和病理学等方面进行了研究。其中6人有进行性神经症状,所有患儿都有血清维生素E浓度降低。对两例死亡病例进行了详细神经病理学检查,其表现与维生素E缺乏动物的所见相似。作者推测,慢性肝病患儿神经症状是慢性维生素E缺乏所致。所有病儿均在婴儿期经剖腹探查确诊为阻塞性胆道疾病,其中3例死亡,余4例现年8～15岁,因出
The author of seven cases of children with chronic obstructive liver disease from the clinical, laboratory and pathological aspects of the study. Six of them had progressive neurological symptoms and all had a reduced serum vitamin E concentration. A detailed neuropathological examination was performed on two deaths and showed similar findings to those found in vitamin E deficient animals. The authors speculate that children with chronic liver disease neurological symptoms caused by chronic vitamin E deficiency. All sick children were diagnosed as obstructive biliary disease by exploratory laparotomy during infancy, 3 of them died and 4 of them were 8 to 15 years old