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目的分析血清降钙素原在治疗AECPHD患者中的指导意义。方法从我院AECPHD患者中随机选取75例作为研究对象,并将其分为实验组与对照组,实验组有38例,对照组有37例。给予实验组患者在检测血清降钙素原(PCT)水平后确定抗生素治疗方案,而对照组患者则由医师凭借临床经验确定抗生素治疗方案,观察两组患者临床疗效、二重感染情况以及住院、抗生素使用用时。结果实验组与对照组患者的临床总有效率分别为92.11%与72.97%,实验组患者临床疗效优于对照组;实验组患者的二重感染率(5.26%)明显低于对照组(24.32%);对照组患者住院用时、抗生素使用时间均明显多于实验组患者,且P<0.05,差异具有统计学意义。结论分析AECPHD患者的血清降钙素原水平可明确患者使用抗生素治疗方案,明显缩短其抗菌治疗用时,降低二重感染发生几率。
Objective To analyze the guiding significance of serum procalcitonin in the treatment of patients with AECPHD. Methods AECPHD patients from our hospital were randomly selected 75 cases as study subjects, and divided into experimental group and control group, experimental group 38 cases, control group 37 cases. Patients in the experimental group were given antibiotics after the serum procalcitonin (PCT) level was tested, while in the control group, the antibiotic treatment was determined by the physicians based on clinical experience. The clinical efficacy, double infection and hospitalization were observed in two groups. Antibiotic use time. Results The total effective rates of the experimental group and the control group were 92.11% and 72.97% respectively. The clinical efficacy of the experimental group was better than that of the control group. The double infection rate (5.26%) in the experimental group was significantly lower than that of the control group (24.32% ). In the control group, the antibiotic use time was significantly higher in the hospitalized patients than in the experimental group (P <0.05). The difference was statistically significant. Conclusions Analysis of serum procalcitonin levels in patients with AECPHD can be used to identify patients with antibiotic treatment program, significantly shortening its antimicrobial treatment time, reducing the incidence of double infection.