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鼻咽部恶性肿瘤应用放射线治疗可以引起外耳、中耳及咽鼓管的并发症,文献中且有报告迷路受损伤因而产生感音性聋者。作者们对14例鼻咽部恶性肿瘤应用钴放疗的患者进行了随访观察,其原发病包括网状细胞肉瘤1例,淋巴上皮瘤5例,鳞状细胞癌8例,钴照射总量均在5,500拉德以上。结果9例出现了耳合并症,最多见的为渗出性中耳炎,亦可称之为“放射性中耳炎”,在9例中即有7例。另2例发生了外耳道放射性骨坏死并发传导性聋,1
Radiotherapy for nasopharyngeal malignancies can cause complications of the outer ear, middle ear, and eustachian tube. In the literature, it has been reported that the labyrinthine is damaged and thus produces a sensorineural hearing loss. The authors performed follow-up observations on 14 patients with malignant nasopharyngeal neoplasms treated with cobalt radiotherapy. The primary disease included reticulum cell sarcoma in 1 case, lymphoepithelial neoplasia in 5 cases, squamous cell carcinoma in 8 cases, and total cobalt exposure. Above 5,500 rads. Results 9 cases of ear complications occurred, the most common is otitis media exudative, also known as “radioactive otitis media”, 9 cases in 7 cases. In the other 2 cases, radioactive osteonecrosis of the external auditory canal was complicated with conductive hernia. 1