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内皮细胞在血液凝集及纤维蛋白溶解过程中起重要作用。为阐明内皮细胞功能变化与胎盘功能的关系,利用间接指标测量评估内皮细胞功能及正常妊娠晚期与内皮细胞功能有关的血凝及纤溶过程中的变化。随机选出26例健康孕妇,无妊娠并发症及足月时分娩并发症,平均年龄29.5(24～41)岁,平均身高1.68(1.58～1.80)m,孕前平均体重61.2(51～90)kg,33％为吸烟者,73％为初孕妇。常规产前检查时采集血液样本。孕30、33和37周时评估vWF(内皮细胞功能标志物)、尿酸及止血参数。静脉血样
Endothelial cells play an important role in blood coagulation and fibrinolysis. In order to elucidate the relationship between changes in endothelial function and placental function, indirect indices were used to assess the changes of endothelial cell function and the process of hemagglutination and fibrinolysis associated with the function of endothelial cells in the third trimester of pregnancy. Twenty-six healthy pregnant women were randomly selected and had no complications of pregnancy and complications during term term. The average age was 29.5 (ranged from 24 to 41 years) with an average height of 1.68 (1.58 to 1.80) m and an average pregnancy weight of 61.2 (51 to 90) kg 33% were smokers and 73% were first mothers. Blood samples are collected during routine prenatal tests. VWF (endothelial function markers), uric acid, and hemostatic parameters were assessed at 30, 33, and 37 weeks of gestation. Venous blood samples