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目的了解并分析北京市某功能社区职业人群血脂流行趋势及与累积糖尿病发病风险的关系,为功能社区职业人群的健康管理提供依据。方法采用重复测量方差分析和多元Logistic回归对北京某功能社区26~60岁373名职业人群2010—2012年的血脂和空腹血糖重复测量数据进行分析。结果上述职业人群2010—2012年这三年总胆固醇(TC)异常分别占3.49%、4.83%和5.90%,甘油三酯(TG)异常占20.91%、22.79%和21.98%,高密度脂蛋白胆固醇(HDL-C)异常占13.40%、29.76%和21.72%,低密度脂蛋白胆固醇(LDLC)异常占0.54%、2.41%和3.49%,空腹血糖异常占1.07%、1.34%和2.95%。男性TC平均水平随年份和年龄变化呈升高的趋势(P<0.01)。不同年份TG平均水平男性均高于女性(P<0.01),HDL-C平均水平男性均低于女性(P<0.01)。Logistic回归分析显示,高龄者发生糖尿病的风险是低龄者发生糖尿病的风险的1.165倍,TG异常者发生糖尿病的风险是TG正常者发生糖尿病的风险的2.987倍。结论某功能社区职业人群血脂总体上有上升的趋势,高甘油三酯水平是糖尿病发病风险的相关因素,多年的血脂连续监测数据能对糖尿病发病风险的预测提供更多信息。
Objective To understand and analyze the relationship between the prevalence of blood lipid and the risk of cumulative diabetes in a functional community in Beijing and provide the basis for the health management of occupational groups in functional communities. Methods Using repeated measures ANOVA and multivariate Logistic regression, the data of lipids and fasting blood glucose in 373 occupational population aged 26-60 years in a functional community in Beijing from 2010 to 2012 were analyzed. Results The above-mentioned occupational groups accounted for 3.49%, 4.83% and 5.90% of total cholesterol (TC) abnormalities in the three years from 2010 to 2012 respectively. The abnormal triglycerides (TG) accounted for 20.91%, 22.79% and 21.98% of the total. High density lipoprotein cholesterol (HDL-C) accounted for 13.40%, 29.76% and 21.72% respectively. Abnormal LDL cholesterol accounted for 0.54%, 2.41% and 3.49%, fasting blood glucose abnormalities accounted for 1.07%, 1.34% and 2.95%, respectively. The mean level of TC in males tended to increase with age and age (P <0.01). The average TG level in different years was higher than that in female (P <0.01), and the average level of HDL-C in male was lower than that in female (P <0.01). Logistic regression analysis showed that the risk of developing diabetes in the elderly was 1.165 times of the risk of developing diabetes in the elderly and the incidence of diabetes in the TG abnormal was 2.987 times of the risk of developing diabetes in the normal TG. Conclusion The blood lipid level of occupational population in a functional community generally has an upward trend. The level of triglyceride is a related factor for the risk of diabetes mellitus. Continuous monitoring of blood lipids for many years can provide more information on the prediction of the risk of diabetes.