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目的 :研究脑梗塞患者不同时期血清 C-反应蛋白 (CRP)水平及其与病情的严重性及预后的关系。方法 :对病程在 2周以内的脑梗塞 90例在入院时及 1周后进行血清 CRP水平的测定 ,应用美国国立卫生研究院卒中量表及Barthel指数记分对入选患者在入院时及 3个月后的神经功能缺损程度进行评分。结果 :病后 2周内的 CRP水平低于再过 1周的 CRP水平 ,前者与患病当时及病后 3个月神经功能缺损的严重程度显著相关 (P<0 .0 1) ,而后者则无此相关。结论 :根据脑梗塞患者病后 2周内的 CRP水平可以对病情的严重性及预后进行判定。
Objective: To study the relationship between serum C-reactive protein (CRP) levels and the severity and prognosis of patients with cerebral infarction at different stages. Methods: Serum CRP levels were measured in 90 cases of cerebral infarction within 2 weeks after admission. Serum CRP levels were measured at admission and at 3 months using the National Institutes of Health Stroke Scale and Barthel Index score After the degree of neurological deficits were scored. Results: The level of CRP within 2 weeks after the illness was lower than that of CRP after 1 week. The former was significantly associated with the severity of neurological deficits at the time of illness and after 3 months (P <0.01), while the latter No such correlation. Conclusion: The severity and prognosis of patients with cerebral infarction can be judged according to the level of CRP within 2 weeks after their illness.