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目的了解北京市房山区健康人群流行性腮腺炎(以下简称流腮)抗体水平,为采取有效的流腮预防控制措施提供科学依据。方法按容量比例概率抽样法,通过调查问卷收集140名研究对象的人口学特征、含流腮成分疫苗免疫史等信息;并采集其静脉血5 ml,用ELASA方法检测流腮Ig G抗体水平。结果 140名调查对象流腮抗体阳性率为56.43%,抗体几何平均滴度(GMT)为69.96 IU/ml;不同性别、户籍、接种不同剂次含流腮成分疫苗流腮抗体阳性率无差异,差异无统计学意义;不同年龄组、职业间抗体阳性率有差异,差异有统计学意义。流腮抗体阳性率随年龄增长呈现出单峰型,5~10岁组为最高峰(72.22%);学生抗体阳性率最高(67.90%);接种2剂含流腮成分疫苗者流腮抗体阳性率最高(75.00%)。结论房山区健康人群抗体阳性率偏低,各类人群免疫水平高低不一。提示在以后工作中要针对重点人群,采取有效防控措施,建立更加安全牢固的免疫预防屏障。
Objective To understand the antibody levels of mumps in healthy population in Fangshan District, Beijing, and to provide a scientific basis for effective prevention and control of flow gills. Methods According to the method of volume proportional probability sampling, the demographic characteristics of 140 subjects and the immunization history of cheek composition vaccine were collected from the questionnaires. 5 ml venous blood samples were collected and Ig G antibody levels were detected by ELASA. Results The positive rate of streptococcal antibody in the 140 subjects was 56.43% and the geometric mean antibody titer (GMT) was 69.96 IU / ml. There was no difference in the positive rate of mumps antibody in the cheek component vaccines of different sex, household registration and inoculation, The difference was not statistically significant; different age groups, occupational antibody positive rates were different, the difference was statistically significant. The positive rate of mumps antibody showed a unimodal pattern with age, the highest peak (72.22%) in the age group of 5 to 10 years, the highest positive rate of antibody (67.90%), the positive rate of mumps antibody The highest rate (75.00%). Conclusion The positive rate of antibody in Fangshan healthy people is low, and the immunity levels of all kinds of people are different. Prompted in the future work should focus on key populations, to take effective prevention and control measures to establish a more secure and secure immune prevention barrier.