化疗是临床治疗恶性肿瘤的主要手段之一。化疗强度的增加可更加迅速地消除体内的肿瘤负荷和缓解期的微小残留病灶（ＭＲＤ），有助于提高患者的长期无病生存率（ＤＦＳ）。由于头颈部恶性肿瘤解剖部位的复杂性，对晚期难于手术切除及放疗不敏感的患者来说，化疗越来越受到... Chemotherapy is one of the main methods for clinical treatment of malignant tumors. Increased intensity of chemotherapy can more rapidly eliminate tumor burden in vivo and minimal residual disease (MRD) during remission, helping to increase long-term disease-free survival (DFS) in patients. Due to the complexity of the anatomy of head and neck malignancies, chemotherapy is becoming more and more difficult for patients who are refractory to surgery and radiotherapy in the late stages.