论文部分内容阅读
目的 :观察血清SAA、CRP、IL - 6、IL - 8及SIL - 2R在急性胰腺炎病程中的变化 ,探讨SAA在急性胰腺炎发生发展中的辅助诊断及疾病严重度评价的实用价值。方法 :SAA、CRP定量检测 :采用乳胶增强速率散射比浊法。IL - 6、IL - 8、SIL - 2R水平采用ABC -ELISA法检测。结果 :急性重症胰腺炎患者五项指标显著高于急性轻症胰腺炎及正常对照组 (p <0 0 1 )。同时血清SAA水平与CRP、IL - 6、IL - 8水平呈显著相关 (p <0 0 1 )。急性轻症胰腺炎组SAA、CRP、IL - 6水平高于正常对照组 (p <0 0 5 )。 结论 :联合检测血清SAA、CRP、IL - 6、IL - 8水平对判断急性重症胰腺炎的严重程度及提示急性胰腺炎坏死性形成具有重要参考价值。在急性胰腺炎的病程中SAA的检测价值优于CRP。
OBJECTIVE: To observe the changes of serum SAA, CRP, IL - 6, IL - 8 and SIL - 2R in the course of acute pancreatitis and to explore the practical value of SAA in the diagnosis and severity evaluation of acute pancreatitis. Methods: Quantitative detection of SAA and CRP: Latex enhanced rate nephelometry. The levels of IL - 6, IL - 8 and SIL - 2R were detected by ABC - ELISA. Results: Five indicators of acute severe pancreatitis were significantly higher than those of acute mild pancreatitis and normal control group (p <0.01). At the same time, serum SAA level was significantly correlated with CRP, IL - 6 and IL - 8 levels (p <0.01). The levels of SAA, CRP and IL - 6 in acute mild pancreatitis group were higher than those in normal control group (p <0.05). Conclusion: The combined detection of serum SAA, CRP, IL - 6 and IL - 8 levels has important reference value in judging the severity of acute severe pancreatitis and suggesting the formation of acute pancreatitis necrosis. SAA is superior to CRP in the course of acute pancreatitis.