前列腺素是哺乳动物肾脏中调节血流动力学和排泄功能的重要物质。本文研究肾脏和肾外的前列腺素对高血压患者肾脏钠负荷的调节作用。作者对高血压患者和年龄配对的血压正常者各10例在对照状况(钠摄入80mEq/日)、单纯盐负荷(480mEq/日)或盐负荷加服消炎痛或苏灵达(Sulindac,抗炎药—译注)后进行研究。消炎痛普遍性地抑制前列腺素合成,而 Prostaglandins are important substances in the mammalian kidney that regulate hemodynamics and excretion. This article studies renal and extrarenal prostaglandins on the regulation of renal sodium load in hypertensive patients. The authors of 10 cases of hypertensive patients and age-matched normotensive patients in the control condition (sodium intake 80mEq / day), salt load alone (480mEq / day) or salt load plus indomethacin or Sulindac (anti Inflammatory drugs - Annotation) after the study. Indomethacin suppresses prostaglandin synthesis generally