论文部分内容阅读
目的 探讨局部不良型宫颈癌的综合治疗。方法 4 0例宫颈癌术前行常规综合放疗 ,A点剂量 >70Gy 30例 ,6 0～ 70Gy 7例 ,5 0～ 5 9Gy 2例 ,4 4Gy 1例。放疗后 1～ 8周行筋膜外子宫切除术 15例 ,次广泛子宫切除术 2 3例 ,广泛性子宫切除加盆腔淋巴结清扫术 2例。结果 2例死于夹杂症 ,12例死于肿瘤未控或复发。 3年生存率为 74 .9% ,5年生存率为 6 6 .8%。 5 0 %治疗失败发生于治疗后 1年内 ,2年内死亡率为 9/ 12 (75 .0 % )。 3例发生术后并发症 ,均经保守治疗痊愈。结论 放疗后辅以近期子宫切除的综合治疗 ,对治疗局部不良型宫颈癌有其合理性及可行性
Objective To investigate the comprehensive treatment of locally advanced cervical cancer. Methods Forty cases of cervical cancer were treated with conventional radiotherapy. A point dose was> 70Gy in 30 cases, 60-70Gy in 7 cases, 50-559Gy in 2 cases and 4 4Gy in 1 case. One to eight weeks after radiotherapy, 15 cases were treated with extra-fascicular hysterectomy, 23 cases with extensive hysterectomy, and 2 cases with extensive hysterectomy and pelvic lymphadenectomy. Results of 2 cases died of inclusion disease, 12 cases died of tumor uncontrolled or recurrence. The 3-year survival rate was 74.9% and the 5-year survival rate was 6.6%. Fifty percent of treatment failures occurred within one year of treatment, with a 9-year (75.0%) 2-year mortality rate. 3 cases of postoperative complications, were cured by conservative treatment. Conclusion Radiotherapy combined with recent hysterectomy combined treatment of local adverse cervical cancer has its rationality and feasibility