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目的:观察联合应用甲氨蝶呤与米非司酮治疗异位妊娠的临床效果。方法:选择70例异位妊娠患者,随机分为对照组与研究组各35例,给予对照组米非司酮治疗,研究组采用甲氨蝶呤与米非司酮联合治疗,观察两组治疗后的治疗效果以及不良反应发生情况。结果:经治疗后,研究组患者的住院时间以及血β-HCG明显优于对照组;且研究组治疗有效率明显优于对照组,组间比较差异显著,具有统计学意义(P<0.05)。结论:给予异位妊娠患者甲氨蝶呤与米非司酮联合治疗的效果较为确切,值得推广和应用。
Objective: To observe the clinical effect of combination of methotrexate and mifepristone in the treatment of ectopic pregnancy. Methods: Seventy patients with ectopic pregnancy were randomly divided into control group and study group (n = 35), treated with mifepristone. The study group was treated with methotrexate combined with mifepristone, and the two groups were treated After the treatment and adverse reactions occur. Results: After treatment, the hospitalization time and serum β-HCG in the study group were significantly better than those in the control group. The effective rate of the study group was significantly better than that of the control group, with significant difference between the two groups (P <0.05) . Conclusion: The combination of methotrexate and mifepristone in patients with ectopic pregnancy is more accurate and worthy of promotion and application.