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目的探讨肾动脉狭窄的临床特征,提高诊断水平。方法对2001—2004年东南大学附属中大医院经肾动脉造影确诊的42例患者其肾动脉狭窄临床表现和实验室及器械检查结果进行回顾性分析,并与同期肾动脉造影检查阴性的153例患者进行比较。结果肾动脉狭窄组与非肾动脉狭窄组比较,两组冠心病、高血压、高脂血症、肾功能不全、低钾血症、左心室肥厚发生率差异有显著性(P<0.05)。将冠心病、顽固性高血压、双肾不等大、血管杂音等主要病症进行分析,发现冠心病、顽固性高血压、血管杂音诊断肾动脉狭窄敏感性(60.3%)、阳性预测值(91.7%)和阴性预测值(90.0%)均为最高。结论冠心病、顽固性高血压、血管杂音3个病症对临床早期发现肾动脉狭窄具有重要意义。
Objective To investigate the clinical features of renal artery stenosis and to improve the diagnostic level. Methods The clinical manifestations, laboratory findings and laboratory findings of 42 patients with renal artery stenosis confirmed by renal artery angiography at the Affiliated Zhongda Hospital of Southeast University during 2001-2004 were analyzed retrospectively. The results were compared with 153 cases with negative renal angiography Patients were compared. Results There were significant differences in the incidence of coronary heart disease, hypertension, hyperlipidemia, renal insufficiency, hypokalemia and left ventricular hypertrophy between the group of renal artery stenosis and non-renal artery stenosis (P <0.05). Coronary heart disease, refractory hypertension, unequal renal tubules, vascular malocclusion and other major conditions were analyzed and found coronary artery disease, intractable hypertension, vascular noise diagnosis of renal artery stenosis (60.3%), positive predictive value (91.7 %) And negative predictive value (90.0%) were the highest. Conclusion Coronary heart disease, intractable hypertension and vascular murmur are of great significance for early detection of renal artery stenosis.