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目的:探讨应用高频电刀烧灼置泵栓塞等方法综合治疗结直肠癌多发肝转移癌的疗效。方法:选择2005年1月至2014年12月收治的结直肠癌多发肝转移癌患者46例,应用切除原发结直肠癌,高频电刀烧灼置泵栓塞等综合治疗多发肝转移癌,为手术综合治疗组。回顾分析2001年1月至2013年12月结直肠癌多发肝转移癌45例患者资料。应用非手术综合治疗,为非手术综合治疗组。2组肝脏多发转移病灶,分布于左右叶,大于10个转移灶,对比分析2组治疗后生存率。结果:手术综合治疗组1年、2年、3年、4年生存率分别为89%(41/46)、13%(6/46)、2%(1/46)、0(0/46)。非手术综合治疗组1年、2年生存率分别为11%(5/45)、0(0/45)。2组1年、2年生存率比较差异有统计学意义(P<0.01)。结论:高频电刀烧灼置泵栓塞等综合治疗结直肠癌多发肝转移癌有较好的治疗效果,提高了患者的生存率。
Objective: To explore the use of high-frequency electrocautery burned pump embolization and other methods of comprehensive treatment of colorectal cancer multiple liver metastases. Methods: Forty-six patients with multiple metastases of colorectal cancer admitted from January 2005 to December 2014 were enrolled in the study. Multiple primary hepatic metastases were treated by resection of primary colorectal cancer and high-frequency electrocautery cauterization and pump embolization Comprehensive surgical treatment group. The data of 45 patients with multiple colorectal cancer with metastatic liver cancer from January 2001 to December 2013 were retrospectively analyzed. Application of non-surgical treatment, non-surgical treatment group. Two groups of multiple liver metastatic lesions, located in the left and right leaves, more than 10 metastases, comparative analysis of two groups after treatment survival rate. Results The survival rates at 1 year, 2 years, 3 years and 4 years in the comprehensive treatment group were 89% (41/46), 13% (6/46), 2% (1/46), 0 (0/46) ). The 1-year and 2-year survival rates of non-surgical treatment group were 11% (5/45) and 0 (0/45), respectively. The 1-year and 2-year survival rates in the two groups were significantly different (P <0.01). Conclusion: The high-frequency electrocautery burned pump embolization and other comprehensive treatment of multiple colorectal cancer with liver metastases have a better therapeutic effect and improve the survival rate of patients.