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目的:探讨综合内科老年住院患者潜在不适当用药（PIM）发生情况及其影响因素。方法:收集北京同仁医院综合内科2019年1月1日至12月31日出院老年患者（≥65岁）的病历资料，分别采用美国老年医学会2019年版Beers标准（2019 AGS Beers标准）和《中国老年人潜在不适当用药判断标准（2017年版）》（2017中国标准）评价患者住院期间的PIM发生情况，并将患者按性别、年龄（7 d是发生PIM的危险因素（均n P<0.001）。n 结论:2019年我院综合内科超过半数的老年住院患者存在PIM，高龄、联用多种药物、合并多种疾病和住院时间超过1周是PIM的危险因素。“,”Objective:To explore the occurrence of potentially inappropriate medication (PIM) and its influencing factors in elderly inpatients in department of general internal medicine.Methods:The medical record data of elderly patients (≥65 years) discharged from the Department of General Internal Medicine in Beijing Tongren Hospital, Capital Medical University between January 1st and December 31st, 2019 were collected. The occurrence of PIM in these patients during hospitalization was evaluated according to the 2019 Beers Criteria of the American Geriatric Association (2019 AGS Beers criteria) and Criteria of Potentially Inappropriate Medications for Older Adults in China (2017 Chinese criteria). Patients were grouped according to their gender, age (7 days) were risk factors for PIM (n P<0.001 for all).n Conclusions:The incidence of PIM in elderly inpatients in Department of General Internal Medicine in our hospital were similar using the 2 criteria, but the drugs involved were different. Using different criteria to evaluate PIM can complement each other and help pharmacists find more PIM.