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目的 :观察中药消瘕方联合介入治疗乳腺癌肝转移中远期疗效。方法 :将60例乳腺癌肝转移患者,随机分为2组,各30例。对照组给予介入治疗,观察组在对照组基础上加用中药消瘕方治疗。观察2组患者的临床治疗效果,对患者实施为期2年的随访调查,记录所有患者远期生存率。结果:总有效率观察组43.3%,对照组16.7%,2组比较,差异有统计学意义(P<0.05)。1年的生存率观察组70.0%,对照组43.3%;2年生存率观察组36.7%,对照组16.7%,2组比较,差异均有统计学意义(P<0.05);观察组平均生存期显著高于对照组,差异有统计学意义(P<0.05)。恶心呕观察组20.0%,对照组36.7%;食欲不振观察组30.0%,对照组53.3%;腹泻观察组13.3%,对照组30.0%,2组比较,差异有统计学意义(P<0.05)。结论:乳腺癌肝转移患者采用中药消瘕方联合介入治疗,疗效显著,可提高患者的生存质量。
Objective: To observe the long-term curative effect of traditional Chinese medicine Xiaoyaofang combined with interventional therapy in the treatment of liver metastasis of breast cancer. Methods: Sixty cases of liver metastases from breast cancer were randomly divided into two groups (n = 30 in each group). The control group was given interventional treatment. The observation group was treated with Chinese medicine Xiaoyu Fang on the basis of the control group. The clinical effects of the two groups were observed. A 2-year follow-up survey of the patients was performed to record the long-term survival of all patients. Results: The total effective rate was 43.3% in the observation group and 16.7% in the control group. There was significant difference between the two groups (P <0.05). The 1-year survival rate was 70.0% in the observation group and 43.3% in the control group. The 2-year survival rate was 36.7% in the observation group and 16.7% in the control group. There was significant difference between the two groups (P <0.05) Significantly higher than that of the control group, the difference was statistically significant (P <0.05). The incidence of nausea and vomiting was 20.0% in the observation group and 36.7% in the control group; 30.0% in the observation group with appetite loss and 53.3% in the control group; 13.3% in the diarrhea observation group and 30.0% in the control group. There was significant difference between the two groups (P <0.05). Conclusion: The patients with liver metastasis of breast cancer treated with traditional Chinese medicine Xiaoya Recipe combined with interventional therapy, the curative effect is significant, can improve the quality of life of patients.