“动物实验”是病理学研究的一种重要方法。我国早在东晋末期就已萌芽。如《南史》称刘裕青年时(四世纪八十年代),射伤了一个蛇妖,蛇妖为了治伤,就去寻找一味药草。在寻找期间,为刘裕所见,于是刘裕就用这味药草来治金创,即收到良好的效果。刘裕的部下刘敬叔,在他所著的《异苑》里说:“青州刘烬,宋元嘉中射一獐,剖五脏,以其草(鹿活草)塞之,既然而起。烬怪而拔草,便倒。如此三度,烬密录此草种之,主伤折多愈”。文中的“如此三度”,类似现在动物实验的重复。唐代,张鷟(约660～740)《朝野长载》说:“医书言:虎中药箭食青泥,野猪中药箭豗荠苨而食,雉被鹰伤,以地黄叶贴之。又矾石可以害鼠,张鷟曾 “Animals” is an important method for pathological studies. China had sprouted as early as the late Eastern Jin Dynasty. Such as “Southern History,” said Liu Yu youth (in the eighties of the eighties), shooting a snake demon, snake demon to cure the injury, they go to find blindly herbs. During the search, Liu Yu was seen, so Liu Yu used this herb to cure Jin Chuang, which received good results. Liu Yu’s subordinate Liu Jingshu said in his book “Yi Yuan”: “Qingzhou Liu Ye and Song Yuanjia shot a shot and cut the five internal organs, and their grass (deer live grass) was stuffed. Grass, then down. Such three degrees, meticulously recorded this kind of grass, the main injury more than more.“ The ”three degrees“ in the text is similar to the repetition of animal experiments. In the Tang dynasty, Zhang Jian (circa 660-740), ”Long Life in the Wilderness,“ said: ”America’s book says: Tiger Herbalism eats green clay, wild boar medicine is smashed and eaten, crickets are injured by an eagle, and it is attached to yellow leaves. Meteorites can kill rats, Zhang Yizeng