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1962到1983年22年间共手术治疗小细胞肺癌50例,其中27例切除(包括4例姑息切除),1例手术死亡。手术切除后4例5年以上健在(其中3例10年健在)。剖胸探查者无5年健在病例。Ⅰ期患者的5年生存率为17.6％,10年生存率为11.8％;Ⅱ期无2年以上生存者;Ⅲ期仅1例10年以上健在。无淋巴结转移的预后优于有转移者。症状期超过半年者切除率甚低。凡术前病理已证实为小细胞未分化癌,尤其是中心型。不适于手术治疗。作者认为辅助放疗和化疗,确能延长患者的生存期,故根治术后皆应辅助放疗和化疗,以期提高疗效。
In the 22 years from 1962 to 1983, 50 cases of small cell lung cancer were treated surgically. 27 cases (including 4 cases of palliative resection) and 1 case died of surgery. After surgical resection, 4 cases were more than 5 years old (3 of them were 10 years old). The thoracoprosthesis explorer did not have 5 years of life. The 5-year survival rate of stage I patients was 17.6%, and the 10-year survival rate was 11.8%. There were no survivors of stage 2 with more than 2 years of survival. In stage III, only 1 case with more than 10 years survived. The prognosis without lymph node metastasis was better than with metastasis. The resection rate is very low when the symptoms last more than six months. All preoperative pathology has been confirmed as small cell undifferentiated carcinoma, especially central type. Not suitable for surgical treatment. The authors believe that adjuvant radiotherapy and chemotherapy can actually prolong the survival of patients. Therefore, radiotherapy and chemotherapy should be assisted after radical surgery in order to improve the efficacy.