论文部分内容阅读
目的观察阿奇霉素辅治儿童传染性单核细胞增多综合征的临床治疗效果。方法选择2014年1月-2017年1月收治的儿童传染性单核细胞增多综合征患儿50例,根据随机数字表法分为2组各25例。对照组给予常规治疗,干预组在对照组治疗的基础上给予阿奇霉素治疗。比较2组治疗效果、丙氨酸氨基转移酶(ALT)水平、白细胞计数、退热时间、咽部脓性渗出消失时间、淋巴结恢复正常时间及住院时间。结果干预组总有效率为100.0%高于对照组的80.0%,差异有统计学意义(χ~2=8.041,P<0.05)。干预前2组ALT水平、白细胞计数比较差异均无统计学意义(P>0.05);干预后2组ALT水平、白细胞计数均降低,且干预组低于对照组,差异均有统计学意义(P<0.05)。干预组退热时间、咽部脓性渗出消失时间、淋巴结恢复正常时间、住院时间均短于对照组,差异均有统计学意义(P<0.05)。结论在常规治疗基础上给予阿奇霉素治疗儿童传染性单核细胞增多综合征临床效果显著,可有效促进临床症状消退,促使淋巴结恢复正常,改善ALT水平、白细胞水平,缩短疗程,值得临床推广。
Objective To observe the therapeutic effect of azithromycin on infectious mononucleosis syndrome in children. Methods Fifty children with infectious mononucleosis syndrome in children who were admitted from January 2014 to January 2017 were divided into 2 groups of 25 cases according to the random number table. Control group given conventional treatment, intervention group on the basis of the control group treated with azithromycin. The therapeutic effect, ALT level, leukocyte count, antipyretic time, disappearance of pharyngeal purulent exudate, normal lymph node recovery time and hospital stay were compared between the two groups. Results The total effective rate in the intervention group was 100.0%, which was significantly higher than that in the control group (χ ~ 2 = 8.041, P <0.05). There was no significant difference in ALT level and leukocyte count between the two groups before intervention (P> 0.05). The level of ALT and WBC decreased after intervention in intervention group, and the difference was statistically significant (P <0.05). In the intervention group, the time of fever, the disappearance of pharyngeal purulent exudation, the normal time of lymph node recovery, and the length of hospital stay were all shorter than those in the control group (P <0.05). Conclusion The treatment of children with infectious mononucleosis syndrome on the basis of routine treatment is clinically effective in treating children with infectious mononucleosis syndrome, which can effectively promote the regression of clinical symptoms, promote the normalization of lymph nodes, improve the level of ALT, leukocyte and shorten the course of treatment.