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目的研究分析消化内科门诊治疗胃食管反流病的措施与临床效果。方法 86例消化内科门诊收治的胃食管反流病患者,随机分为对照组和观察组,每组43例。对照组应用雷尼替丁进行治疗,观察组则在对照组治疗基础上联合使用奥美拉唑治疗。对比两组患者临床效果。结果观察组治疗总有效率95.3%显著高于对照组76.7%,差异具有统计学意义(P<0.05)。治疗前两组症状积分比较差异无统计学意义(P>0.05),治疗后两组症状积分均较治疗前改善,且观察组改善情况优于对照组,差异均具有统计学意义(P<0.05)。观察组不良反应发生率6.98%与对照组9.30%比较差异无统计学意义(P>0.05)。结论消化内科门诊治疗胃食管反流病患者给予雷尼替丁的同时联合使用奥美拉唑能显著提高临床治疗有效率,改善患者的临床症状,且还不会增加药物不良反应,可在基层推广应用。
Objective To analyze and evaluate the clinical efficacy and outcomes of gastroenterology outpatient treatment of gastroesophageal reflux disease. Methods A total of 86 patients with gastroesophageal reflux disease admitted to the Department of Gastroenterology were randomly divided into control group and observation group, with 43 cases in each group. The control group was treated with ranitidine. The observation group was treated with omeprazole in combination with the control group. The clinical effects of two groups were compared. Results The total effective rate of observation group was 95.3%, which was significantly higher than that of control group (76.7%), the difference was statistically significant (P <0.05). There was no significant difference in symptom scores between the two groups before treatment (P> 0.05). After treatment, the symptom scores of both groups improved compared with those before treatment, and the improvement in the observation group was better than that in the control group (P <0.05) ). The incidence of adverse reactions in the observation group was 6.98% compared with 9.30% in the control group, but there was no significant difference (P> 0.05). Conclusions Gastroesophageal reflux disease patients treated with ranitidine combined with omeprazole in patients with gastroesophageal reflux disease can significantly improve the efficiency of clinical treatment and improve the clinical symptoms of patients, and will not increase the adverse drug reactions, but at the grassroots level Promote the application.