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目的探讨产后阴道菌群分布情况及乳杆菌活菌胶囊治疗的疗效。方法选择200例在桐乡市妇幼保健院分娩的产妇,在分娩前与分娩后6周检测产妇的阴道pH,并对阴道分泌物进行细菌培养。比较分娩前后产妇的阴道pH值、乳酸杆菌检出率。根据患者意愿将未患有阴道炎的产妇分为观察组与对照组,观察组予以乳杆菌活菌胶囊治疗,每天1次,每次1粒,连用10d,对照组不采取任何治疗,分别在分娩后3个月、6个月检测产妇的阴道pH,并对阴道分泌物进行细菌培养,比较两组阴道pH值及乳酸杆菌检出率的变化情况及细菌性与念珠菌性阴道炎的发病率,探讨乳杆菌活菌胶囊的疗效。结果分娩后6周产妇的阴道pH明显高于分娩前(P<0.05),而阴道乳酸杆菌检出率却低于分娩前(χ2=73.87,P<0.01);产妇产后6周阴道炎患病率为11.0%,分娩后3个月与分娩后6个月,两组产妇阴道pH均较治疗前下降(P<0.05或P<0.01),且观察组的下降幅度大于对照组(P<0.05),而两组产妇阴道乳酸杆菌检出率却较治疗前增多(χ~2=20.15、36.27,3.88、6.30,P<0.05或P<0.01),且观察组的增多幅度大于对照组(χ~2=3.98、8.66,P<0.05或P<0.01);分娩6个月后观察组细菌性与真菌性阴道炎发病率低于对照组(χ~2=24.79,P<0.01)。结论产妇产后会出现阴道菌群紊乱,阴道pH上升,乳酸杆菌检出率下降,阴道炎患病率上升,采用乳杆菌活菌胶囊干预治疗能有效的平衡阴道菌群,减少产妇产后阴道炎的发生,是一种安全有效的治疗方法。
Objective To investigate the distribution of postpartum vaginal flora and the effect of Lactobacillus live capsule treatment. Methods Two hundred pregnant women delivered at Tongxiang MCH hospital were selected. The vaginal pH of the pregnant women was measured before delivery and 6 weeks after delivery. The vaginal secretions were cultured in vitro. Comparison of vaginal pH before and after childbirth, lactobacillus detection rate. The patients without vaginitis were divided into observation group and control group according to the wishes of the patients. The observation group was treated with Lactobacillus live capsule once a day for 10 days, without any treatment in the control group Vaginal pH was measured at 3 months and 6 months after delivery, and bacterial culture was performed on vaginal secretions. Vaginal pH and the detection rate of lactobacilli were compared between the two groups, and the incidence of bacterial and candidal vaginitis Rate, to explore the efficacy of Lactobacillus live bacteria capsule. Results The vaginal pH of maternal postpartum 6 weeks after delivery was significantly higher than that before delivery (P <0.05), while the detection rate of lactobacilli was lower than that before delivery (χ2 = 73.87, P <0.01) (P <0.05 or P <0.01), and the decreasing rate in the observation group was larger than that in the control group (P <0.05) ), While the detection rate of vaginal lactobacilli in both groups was higher than that before treatment (χ ~ 2 = 20.15,36.27,3.88,6.30, P <0.05 or P <0.01), and the increasing rate in the observation group was more than that in the control group ~ 2 = 3.98, 8.66, P <0.05 or P <0.01). The incidence of bacterial and fungal vaginitis in observation group was lower than that in control group 6 months after delivery (χ ~ 2 = 24.79, P <0.01). Conclusion Maternal postpartum vaginal flora will be disorder, vaginal pH increased, the detection rate of lactobacilli decreased, the prevalence of vaginitis increased, the use of Lactobacillus live bacteria capsule treatment can effectively balance the vaginal flora, reduce maternal postpartum vaginitis Happen, is a safe and effective treatment.