前列腺癌是男性泌尿生殖系统常见肿瘤之一 ,内分泌治疗是前列腺癌主要治疗手段 ,但疗效并未达到人们预期的程度 ,且长期治疗副作用多。间断性雄激素阻断治疗是最近前列腺癌治疗研究热点之一。本文就近几年前列腺癌间断性雄激素阻断治疗原理、基础和临床研究、临床应用原则及有关问题作一综述。 Prostate cancer is one of the common tumors of the male genitourinary system. Endocrine therapy is the main treatment of prostate cancer, but the effect has not reached the level expected by people, and many side effects of long-term treatment. Intermittent androgen blockade therapy is one of the hot topics in the treatment of prostate cancer recently. This article in recent years, prostate cancer intermittent androgen block treatment principle, basic and clinical research, clinical application of principles and related issues are reviewed.