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目的观察胸腔内中心静脉导管留置引流并灌注药物治疗恶性胸腔积液的疗效。方法对36例恶性胸腔积液患者应用Arrow中心静脉导管胸腔穿刺置管引流,将顺铂(DDP)及天地欣(LNT)稀释后注入胸腔内治疗,每周2次。结果完全缓解(CR)14例,部分缓解(PR)18例,总有效率(CR+PR)为88.89%,毒副反应轻,主要为轻度消化道反应和一过性发热胸痛。结论该方法简便易行、安全,腔内给药副作用低,能有效控制恶性胸腔积液,值得临床推广使用。
Objective To observe the curative effect of intrathoracic central venous catheter indwelling drainage and drug infusion in the treatment of malignant pleural effusion. Methods Thirty-six patients with malignant pleural effusion were treated with Arrow central venous catheter thoracentesis and catheterized. DDP and LNT were injected into the thoracic cavity twice a week. Results Complete remission (CR) in 14 cases, partial remission (PR) in 18 cases, the total effective rate (CR + PR) was 88.89%, toxic side effects, mainly mild digestive tract reaction and transient fever chest pain. Conclusion The method is simple, safe, and has low side effects of intracavitary administration. It can effectively control malignant pleural effusion and is worthy of clinical promotion.