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目的:观察得必泰联合奥美拉唑、奥硝唑治疗消化性溃疡的临床疗效。方法:将我院收治的120例消化性溃疡患者随机分为观察组60例,对照组60例。观察组患者行得必泰、奥美拉唑、奥硝唑联合治疗,对照组患者行丽珠得乐、奥美拉唑、替硝唑联合治疗。评价2组患者的临床治疗效果及幽门杆菌(Hp)转阴率。结果:观察组患者临床治疗的总有效率为95%,对照组为80%。2组比较,差异具有统计学意义(P<0.05)。观察组患者Hp转阴率为86.67%,对照组为68.33%,2组比较,差异具有统计学意义(P<0.05)。结论:得必泰联合奥美拉唑、奥硝唑治疗消化性溃疡的临床疗效显著,且价廉安全实用。
Objective: To observe the clinical efficacy of DBT combined with omeprazole and ornidazole in the treatment of peptic ulcer. Methods: A total of 120 patients with peptic ulcer admitted to our hospital were randomly divided into observation group (60 cases) and control group (60 cases). Patients in the observation group were treated with omeprazole and ornidazole. Patients in the control group were treated with Livzon, omeprazole and tinidazole. The clinical efficacy and H. pylori (Hp) negative rate in two groups were evaluated. Results: The total effective rate of clinical treatment in observation group was 95% and that in control group was 80%. The difference between the two groups was statistically significant (P <0.05). In the observation group, the Hp negative conversion rate was 86.67% in the control group and 68.33% in the control group. There was significant difference between the two groups (P <0.05). CONCLUSION: The combination of omeprazole and ornidazole in the treatment of peptic ulcer has significant clinical effect and is safe and practical.