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目的探讨氯吡格雷联合阿司匹林治疗心肌梗死的临床疗效。方法选取2013年1月—2015年1月舞钢市职工医院收治的心肌梗死患者90例,按照随机分配原则分为对照组与研究组,各45例。研究组患者予以氯吡格雷联合阿司匹林治疗,对照组患者予以阿司匹林治疗。观察两组患者临床疗效及不良反应(过敏、耳鸣、恶心、呕吐)发生情况。结果研究组患者总有效率高于对照组,差异有统计学意义(P<0.05);两组患者不良反应发生率比较,差异无统计学意义(P>0.05)。结论氯吡格雷联合阿司匹林治疗心肌梗死的临床疗效显著,且不良反应少。
Objective To investigate the clinical effect of clopidogrel combined with aspirin in the treatment of myocardial infarction. Methods Totally 90 patients with myocardial infarction admitted to Wugang Workers Hospital from January 2013 to January 2015 were randomly divided into control group and study group, with 45 cases in each group. Patients in the study group were treated with clopidogrel plus aspirin, and patients in the control group were treated with aspirin. The clinical efficacy and adverse reactions (allergy, tinnitus, nausea and vomiting) in two groups were observed. Results The total effective rate of study group was higher than that of control group, the difference was statistically significant (P <0.05). There was no significant difference between the two groups in the incidence of adverse reactions (P> 0.05). Conclusion Clopidogrel combined with aspirin in the treatment of myocardial infarction significant clinical effect, and adverse reactions.