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[目的]观察桑白皮汤联合西药治疗痰热蕴肺型肺心病疗效。[方法]使用随机平行对照方法,将128例住院患者按抛硬币法简单随机分为两组。对照组64例控制性氧疗、抗感染、解痉、化痰、平喘,磷酸肌酸钠,1g/次,1~2次/d,30~45min内完成静滴。治疗组64例桑白皮汤(法半夏10g,桑白皮15g,紫苏子10g,浙贝母15g,黄芩、北杏仁、麻黄~灸、积实各10g,甘草6g;大便不通加大黄~(后下)10g),1剂/d,水煎400m]L,早晚口服;西药治疗同对照组。连续治疗7d为1疗程。观测临床症状、LVID;RVID;肺动脉压;PaO_2;PaCO_2不良反应。连续治疗4疗程,判定疗效。[结果]治疗组显效29例,有效32例,无效3例,总有效率95.3 1%。对照组显效23例,有效30例,无效11例,总有效率82.81%。治疗组疗效优于对照组(P<0.05)。LVID;RⅥD;肺动脉压;PaO_2;PaCO_2两组均有改善(P<0.01),治疗组改善优于对照组(P<0.01)。[结论]桑白皮汤联合西药治疗痰热蕴肺型肺心病疗效满意,无严重不良反应,值得推广。
[Objective] To observe the curative effect of mulberry white soup and western medicine on phlegm-dampness-lung-type pulmonary heart disease. [Methods] Using randomized parallel control method, 128 inpatients were randomly divided into two groups according to the coin-tossing method. Control group of 64 cases of controlled oxygen therapy, anti-infective, antispasmodic, phlegm, asthma, sodium creatine phosphate, 1g / time, 1 ~ 2 times / d, intravenous infusion completed within 30 ~ 45min. Treatment group, 64 cases of Sangbupi Tang (Pinellia 10g, Morus alba 15g, perilla seed 10g, Fritillaria 15g, skullcap, North almonds, ephedra ~ moxibustion, plot real 10g, licorice 6g; ~ (After the next) 10g), 1 / d, decoction 400m] L, morning and evening oral; western medicine treatment with the control group. Continuous treatment 7d for a course of treatment. Observed clinical symptoms, LVID; RVID; pulmonary arterial pressure; PaO_2; PaCO_2 adverse reactions. Continuous treatment of 4 courses to determine the efficacy. [Results] In the treatment group, 29 cases were markedly effective, 32 cases were effective, 3 cases were ineffective, and the total effective rate was 95.3%. The control group was effective in 23 cases, effective in 30 cases, ineffective in 11 cases, the total effective rate was 82.81%. The treatment group was better than the control group (P <0.05). LVID; RVID; pulmonary arterial pressure; PaO_2; PaCO_2 were improved in both groups (P <0.01), the treatment group improved better than the control group (P <0.01). [Conclusion] Sangbubi decoction combined with western medicine is effective in treating phlegm-damp lung-type pulmonary heart disease without serious adverse reactions and is worth promoting.