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报道罕见的胃癌骨转移8例,其中伴骨髓转移4例,占全部胃癌病例的0.46%(8/1752).椎骨、盆骨、肋骨是好发部位,中上部的BOrrmannⅢ、Ⅳ型浸洞性癌;组织学低分化或呈浸润性生长者,浸润深度超过SS,淋巴结转移≥N2及脉管癌栓等病理类型与本病关系密切。化疗效果不明显,放疗可减轻疼痛,但预后不佳。血清ALP、CEA、HCG消长的动态观察,结合99mTc-MDP骨扫描有助于早期发现。
Reported rare cases of gastric cancer bone metastases in 8 cases, including 4 cases with bone marrow metastasis, accounting for 0.46% (8/1752) of all cases of gastric cancer. The vertebrae, pelvis, and ribs are the predileous sites. BOrrmann III and IV infiltrating carcinoma in the middle and upper parts; histologically poorly differentiated or infiltrative growth; infiltration depth exceeds SS; lymph node metastasis ≥ N2 and vascular tumor embolus and other pathologies The type is closely related to this disease. The effect of chemotherapy is not obvious, radiotherapy can relieve pain, but the prognosis is poor. The dynamic observation of serum ALP, CEA, HCG growth and combined with 99mTc-MDP bone scan can help early detection.