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目的:探讨急诊医护人员新型冠状病毒感染的原因及防护策略。方法:回顾性分析2020年1月5日至3月2日武汉大学中南医院急诊科感染新型冠状病毒医护人员的资料，比较不同条件下急诊医护人员感染情况。结果:共计13例感染新型冠状病毒的急诊医护人员（其中确诊病例12例，疑似病例1例），感染率为17.8%（13/73），其中急诊诊间/抢救室感染率为11.8%（4/34），隔离观察室感染率为20.0%（3/15），隔离病房感染率为25%（6/24）；医生感染率为13.0%（3/23），护士感染率为20.0%（10/50）。13例感染医护人员均有明确的COVID-19确诊或疑似患者接触史，1例无症状感染者通过病原学筛查发现，2020年2月5日之后无新增感染医护人员，所有感染医护人员均治愈。结论:在COVID-19疫情下，急诊医护人员具有较高的职业暴露与感染风险，尤其是隔离区工作人员。科学的防护管理可有效降低急诊科医护人员新型冠状病毒感染风险，保障执业安全。“,”Objective:To analyze the causes of SARS-CoV-2 nosocomial infection among healthcare workers (HCWs) and explore the effective precaution strategies in Emergency Center.Methods:The data of SARS-CoV-2 infected HCWs from January 5 to March 2, 2020 were retrospectively analyzed and compared under different conditions in Emergency Center of Zhongnan Hospital of Wuhan University.Results:Totally 13 SARS-CoV-2 infected HCWs (12 confirmed cases and 1 suspected case) were included in this study. The overall infection rate was 17.8% (13/73). The infection rates in outpatient/rescue room, isolation observation room and isolationin patient ward were 11.8% (4/34), 20.0% (3/15), 25% (6/24), respectively. The infection rate of physician was 13.0% (3/23), and the infection rate of nurse was 20.0% (10/50). All the infected HCWs had the definite exposure with confirmed or suspected COVID-19 patients. One asymptomatic cases were identified by laboratory findings of SARS-CoV-2 infection screening. There was no new confirmed SARS-CoV-2 infected HCWs after February 5, 2020. All the infected HCWs were cured.Conclusions:Under the epidemic of COVID-19, HCWs of Emergency Center have a high risk of occupational exposure and infection, especially for staffs working in COVID-19 isolation units. Scientific prevention and control management can effectively reduce the risk of SARS-CoV-2 infections and ensure the occupational safety for HCWs in Emergency Center.