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OBJECTIVE:To ascertain whether continuous treat-ment with Traditional Chinese Medicine(TCM)com-bined with standardized drug therapy from West-ern Medicine can further reduce the incidence of cardiovascular events in patients with coronary heart disease and angina and reduce the incidence of angina pectoris in patients with coronary heart disease.METHODS:A multicenter,prospective cohort study of 1042 patients in 22 hospitals was conduct-ed.A total of 423 patients with angina pectoris were treated with standardized Western Medicine alone(control group)and 619 with a combination of Chinese and Western Medicine(exposure group).The two groups underwent follow-up for 1 year to establish whether there was any improve-ment in the incidence of cardiovascular events or change in the curative effect.RESULTS:The incidence of primary endpoint events in the combined-exposure group decreased by 0.45%(P>0.05)and the incidence of secondary terminal events decreased by 5.25%in comparison with the control group(P<0.05).The total angina pectoris score clearly decreased in the Western Medicine group over the first 6 months,but the de-cline was more apparent in the combined-expo-sure group.CONCLUSION:Compared with treatment using standardized Western Medicine alone,providing TCM combined with Western medical treatment re-duced the incidence of cardiovascular events in pa-tients with stable angina pectoris(grade Ⅱ end-point)and effectively improved the curative effect.