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目的探讨凝结芽孢杆菌活菌片(商品名:爽舒宝)治疗孕妇功能性腹胀的临床疗效。方法选取193例功能性腹胀的孕妇,随机分为治疗组和对照组,对照组指导注意饮食、加强运动等进行调理,治疗组在上述调理的基础上口服凝结芽孢杆菌活菌片,首次服用6片,以后3片/次,3次/d,疗程为4周。观察孕妇胀气、排气、排便的变化情况以及观察药物不良反应。结果治疗4周后,孕妇胀气、排气、排便情况均得到明显改善,显著优于对照组(t分别为-1.991、-2.548、-1.951,P<0.05)。治疗过程中未发现药物不良反应。结论凝结芽孢杆菌活菌片治疗孕妇功能性腹胀取得了较好的疗效,安全性好,值得临床推广。
Objective To investigate the clinical efficacy of Bacillus coagulans viable tablet (trade name Shuangshuobao) in the treatment of functional bloating in pregnant women. Methods Ninety-three pregnant women with functional abdominal distension were randomly divided into treatment group and control group. The control group was instructed to pay attention to diet, exercise and so on. The treatment group received viable Bacillus coagulans via oral administration on the basis of the above treatment. For the first time, 6 Tablets, after 3 / time, 3 times / d, treatment for 4 weeks. Observation of pregnant women flatulence, exhaust, defecation changes and observe the adverse drug reactions. Results After 4 weeks of treatment, the flatulence, excretion and defecation of pregnant women were significantly improved, which was significantly better than that of the control group (t = -1.991, -2.548, -1.951, P <0.05). Adverse drug reactions were not found during treatment. Conclusion Bacillus coagulans livelobe tablets treatment of pregnant women with functional abdominal distension has achieved good results, good safety, it is worth clinical promotion.