论文部分内容阅读
目的分析丙种球蛋白对病毒性心肌炎治疗的疗效优势,为临床作方法论指导。方法随机选择120例病毒性心肌炎患者,随机分为实验组及对照组各60个。对照组用常规治疗:注意休息,抗生素抗感染,维生素C,每次100～200mg/kg加入10%生理盐水中30ml,缓慢静脉推注,一次/每日;辅酶Q10,1mg/kg/d,口服,促进心肌代谢。实验组在对照组治疗方法基础上加用丙种球蛋白,静脉滴注,治疗一个月以后比较其疗效。结果治疗组心肌酶的恢复较快,症状体征的改善时间明显较对照组短;加用静脉滴注丙种球蛋白组的临床总有效率91.7%显著高于常规治疗的对照组75%,两组间差异均具有统计学意义(P<0.05)。结论丙种球蛋白能保护心肌,有效的治疗病毒性心肌炎,是临床上免疫治疗病毒性心肌炎的实效药物,值得推广。
Objective To analyze the therapeutic effect of gamma globulin on viral myocarditis and provide guidance for the clinical practice. Methods A total of 120 patients with viral myocarditis were randomly divided into experimental and control groups of 60 patients. The control group with conventional treatment: pay attention to rest, anti-infective antibiotics, vitamin C, each 100 ~ 200mg / kg 10% normal saline 30ml, slow intravenous injection, once / daily; coenzyme Q10,1mg / kg / d, Oral, promote myocardial metabolism. Experimental group in the control group on the basis of treatment with gamma globulin, intravenous infusion, after a month of treatment compared its efficacy. Results The recovery of myocardial enzyme in the treatment group was faster and the improvement time of symptoms and signs was shorter than that in the control group. The total effective rate of 91.7% in the group receiving intravenous gamma globulin was significantly higher than that of the control group 75% The difference between the two groups was statistically significant (P <0.05). Conclusion Gamma globulin can protect the myocardium and effectively treat viral myocarditis. It is a practical drug for clinical immunotherapy of viral myocarditis and is worth promoting.