转录因子核因子 ｋｂ是一类能与多种基因启动子部位的ｋｂ位点发生特异性结合并促进转录的蛋白质的总称。它通过调控许多重要的细胞因子 ,粘附分子和趋化因子的基因表达 ,而参与机体的各种免疫及炎症反应。由于核因子 ｋｂ在调控多种炎症因子基因表达上起着重要作用 ,而急性肺 Transcription factor Nuclear factor kappa is a generic term for proteins that specifically bind to and promote transcription at the kb site at various promoter regions. It regulates various immune and inflammatory reactions in the body by regulating the gene expression of many important cytokines, adhesion molecules and chemokines. Since NF-kappaB plays an important role in the regulation of the expression of many inflammatory cytokines, acute lung