为了解烧伤对创面局部 IL-8水平的影响,采用 ELISA 方法检测深Ⅱ度烧伤后创面组织、创面邻近正常皮肤和远离创面的正常皮肤中 IL-8含量。结果表明,烧伤创面组织 IL-8水平(54.59±12.44ng/ml)显著高于创缘正常皮肤(3.01±1.62ng/ml)和远离创面的正常皮肤(1.56±1.33ng/ml),P<0.001。研究提示,烧伤后局部创面组织释放 IL-8显著增多,IL-8的释放具有很强的区域性和针对性,对创面愈合的发展和转归起重要作用。 In order to understand the effect of burn on the local IL-8 level in wounds, IL-8 levels in wounds after deep second degree burn, normal skin adjacent to the wound and normal skin far away from the wound were detected by ELISA. The results showed that the level of IL-8 in burn wound tissue (54.59 ± 12.44ng / ml) was significantly higher than that of normal wound (3.01 ± 1.62ng / ml) and normal skin far away from wound (1.56 ± 1.33ng / ml), P < 0.001. Studies have shown that the release of IL-8 is significantly increased in burn wounds, and the release of IL-8 is highly regional and targeted, which plays an important role in the development and prognosis of wound healing.