论文部分内容阅读
多囊卵巢综合征(PCOS)是育龄妇女常见的内分泌及生殖功能障碍性疾病,影响5%~10%的育龄妇女。该疾病具有异质性,其常见病征有多毛症、痤疮、无排卵、高雄激素血症、多囊卵巢及不孕〔1〕等。在多数情况下,PCOS还包括代谢改变,如胰岛素抵抗、高胰岛素血症、血脂异常和并发肥胖等。此外,PCOS患者代谢糖酵解功能增强,三羧酸循环受抑制,氨基酸水平紊乱等,因而PCOS可导致2型糖尿
Polycystic ovary syndrome (PCOS) is a common endocrine and reproductive dysfunction in women of childbearing age, affecting 5% to 10% of women of childbearing age. The disease has heterogeneity, the common symptoms of hirsutism, acne, anovulation, androgen, polycystic ovary and infertility 〔1〕 and so on. In most cases, PCOS also includes metabolic changes such as insulin resistance, hyperinsulinemia, dyslipidemia and obesity. In addition, PCOS patients with enhanced metabolism of glycolytic function, inhibition of tricarboxylic acid cycle, amino acid levels and other disorders, which PCOS can lead to type 2 diabetes