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目的研究围产儿死亡相关原因，推出相应干预对策，提高围产保健工作，降低围产儿死亡率。方法对宜兴市2007～2012年310例围产儿死亡病例资料进行回顾性分析。结果6年内围产儿平均死亡率5.165‰，其中满28周死胎有196例，占63.33%，其次是新生儿死亡有93例，占30%，死产21例，占6.77%，导致围产儿死亡的主要原因依次为出生缺陷、脐带因素及早产低出生体重。结论加强孕期保健，做好高危孕产妇管理，采取干预措施，做好产前筛查，避免早产，防止妊娠并发症和合并症的发生，降低围产儿死亡率。“,”Objective: To research the related causes of perinatal death , put forward intervention measures , improve the quality of perinatal health care and reduce perinatal mortality. Methods : 310 perinatal deaths in Yixing city from 2007 to 2012 were analyzed retrospectively . Results : The average perinatal mortality was 5.165‰ during the 6 years . Among them ,there were 196 cases of at least 28 weeks stil birth , the proportion of it was 63.33% . Next there were 93 cases of neonatal deaths and 21 cases of stil birth , the proportion of them were 30% and 6.77% . In order of priority, the main reasons of perinatal death are birth defects , umbilical factors and preterm low birth weight. Conclusion: The measures to decrease perinatal mortality include strengthening caring during pregnancy , managing high-risk puerpera wel , taking interventional measures , making the best of pregestational check-up , obviating premature delivery , preventing pregnant complications and combinations .