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患者女,50岁,1986年8月29日初诊。主诉右颊部皮肤肿瘤。1985年7月,因不规则阴道出血,于某医院妇产科就诊,诊断为Ib 期子宫颈癌,施行子宫全切术。自1986年7月上旬,右颊部发现无痛性肿瘤,渐增大。体检:右颊鸽蛋大、下唇大豆大、头顶部拇指大、界限清楚、表面光滑、呈红褐色半球形隆起的非移动性硬性肿瘤。肝脏可及,肋下2横指,两腋下触到数个直径为1.5cm 大小的淋巴结。右侧面神经轻度麻痹。下唇肿瘤全切的组织病理变化,真皮浅层至深层,肿瘤细胞形成浸润性巢,各瘤细胞核大小不等,形态不规则,胞浆颗粒状,明显地呈上皮细胞样,未见角化或腺腔形成。右颊部肿瘤组织相与1985年7月在某医院切除的子宫颈癌组织相相同,并见有与皮肤组织相同特征的肿瘤细咆增殖。子宫和皮肤均诊断为低分化非角化
The female patient, 50 years old, was newly diagnosed on August 29, 1986. Chief complaint of right cheek skin tumors. In July 1985, due to irregular vaginal bleeding, a gynecological department of a hospital was diagnosed with stage Ib cervical cancer and hysterectomy was performed. Since early July 1986, painless tumors have been found in the right cheeks and gradually increased. Physical examination: non-mobile hard tumors with large right cheek pigeons, large soybeans on the lower lip, large thumbs on the top of the head, clear boundaries, smooth surfaces, and red-brown hemispherical bulges. The liver was accessible with 2 lateral ribs pointing, and two lymph nodes with a diameter of 1.5 cm were touched under both jaws. The right facial nerve is slightly paralyzed. The histopathological changes of the full-thickness tumor of the lower lip, the superficial to deep layers of the dermis, and the formation of infiltrative nests of the tumor cells. The size of the nuclei varies from tumor to tumor, and the morphology is irregular. The cytoplasm is granular and apparently epithelial cell-like. No keratinization is observed. Or glandular formation. The tumor tissue of the right cheek is the same as the cervical cancer tissue excised in a hospital in July 1985, and the proliferation of the tumor with the same characteristics as the skin tissue is seen. Both uterus and skin are diagnosed as poorly differentiated nonkeratinized