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目的:探讨连续性肾脏替代疗法和间歇性血液透析疗法治疗尿毒症诱导期的有效性。方法:选取2016年4月至2017年4月在东莞市凤岗医院治疗的初发尿毒症诱导期患者68例,依据治疗方式的不同分成肾脏替代组与血液透析组,每组34例,肾脏替代组行连续性肾脏替代疗法治疗,血液透析组采取间歇性血液透析疗法治疗,观察两组治疗效果。结果:肾脏替代组患者中E/A、左心室舒张末期内径(LVDd)、射血分数(EF)和血液透析组比较,差异具有统计学意义(P<0.05)。肾脏替代组中B型利钠肽(BNP)、β2微球蛋白(β2MG)、血红蛋白(Hb)、C反应蛋白(CRP)指标和血液透析组比较,差异具有统计学意义(P<0.05)。结论:在初发尿毒症患者的诱导期治疗中应用连续性肾脏替代疗法,可以改善患者各项指标
Objective: To investigate the effectiveness of continuous renal replacement therapy and intermittent hemodialysis in the induction of uremia. Methods: From April 2016 to April 2017, 68 patients with initial uremic induction in Fenggang Hospital of Dongguan were enrolled. According to the different treatment methods, they were divided into renal replacement group and hemodialysis group, with 34 cases in each group. Instead of continuous renal replacement therapy, hemodialysis patients were treated with intermittent hemodialysis, and the therapeutic effect was observed in both groups. Results: There were significant differences in E / A, LVDd, EF between the renal replacement group and the hemodialysis group (P <0.05). Compared with hemodialysis group, BNP, β2MG, Hb, C-reactive protein (CRP) in renal replacement group were significantly different (P <0.05). CONCLUSIONS: The use of continuous renal replacement therapy in the induction period of patients with naïve uremia can improve various indicators of patients