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为探讨ｒａｓ癌基因和Ｐ５３抗癌基因表达产物、ＤＮＡ含量及其它临床病理因素对子宫内膜癌预后的影响，本文采用单因素、Ｋａｐｌａｎ－Ｍｅｉｅｒ生存曲线和ＳＰＳＳ多元相关与逐步回归软件将患者年龄、临床期别、病理类型、临床分型、组织学分级、肌层侵犯深度、局部免疫反应、ＤＮＡ指数（ＤＩ）、Ｓ期细胞比率（ＳＰＦ）、增殖指数（ＰＩ）、Ｐ２１荧光指数（Ｐ２１ＦＩ）、Ｐ５３荧光指数（Ｐ５３ＦＩ）和Ｐ５３免疫组织化学表达强度等１３个因素与生存的关系进行了分析。结果表明：Ｐ５３表达强度和临床期别为最有意义的预后指标，Ｐ５３表达强阳性和临床Ⅲ期与短生存期有关；另外，肌层侵犯超过２／３、乳头状腺癌和年龄大也提示不良预后。
In order to investigate the effect of ras oncogene and P53 anti-cancer gene expression, DNA content and other clinicopathological factors on the prognosis of endometrial carcinoma, single-factor, Kaplan-Meier survival curves and SPSS multivariate correlation and stepwise regression software were used to analyze the age , Clinical stage, pathological type, clinical classification, histological grade, muscular invasion depth, local immune response, DNA index (DI), S phase cell ratio (SPF), proliferation index (PI), P21 fluorescence index ), P53 fluorescence index (P53FI) and P53 immunohistochemical expression intensity and other 13 factors and survival were analyzed. The results showed that: P53 expression and clinical stage of the most significant prognostic indicators, P53 strong positive expression and clinical stage Ⅲ and short-term survival; In addition, muscle invasion more than 2/3, papillary adenocarcinoma and older Prompted poor prognosis.