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综合14年间晚期妊娠合并生殖道畸形的69例病例,其发生率为0.28%(69/24514)。异常生育史16例,胎膜早破、早产、产后出血、妊高征及剖宫产率均较同期非生殖道畸形者高,差异有显著性(P<0.05)。围产儿病死率为5.8%,显著高于同期围产儿病死率(1.86%,P<0.01)。新生儿出生体重(x±s)为(3009±362.85)g,明显低于同期出生儿体重(x±s)(3286.62±402.83)g。有3例新生儿畸形死亡,2例分娩畸形儿死亡史。妊娠前诊断生殖道畸形的母婴并发症明显低于产时、产后诊断者(P<0.05)。生殖道畸形的早期诊断是减少母婴并发症的关键,并总结了早期诊断的要点。强调了对生殖道畸形者进行遗传学检查的重要性。
In 69 cases of pregnancy complicated with genital tract deformity in 14 years, the incidence was 0.28% (69/24514). 16 cases of abnormal birth history, premature rupture of membranes, premature birth, postpartum hemorrhage, pregnancy-induced hypertension and cesarean section rate than the same period non-genital malformations, the difference was significant (P <0.05). Perinatal mortality was 5.8%, significantly higher than the perinatal mortality (1.86%, P <0.01). The newborn’s birth weight (x ± s) was (3009 ± 362.85) g, which was significantly lower than that of the newborn at birth (x ± s) (3286.62 ± 402.83) g. There were 3 neonatal malformations and 2 deaths from malformations. Maternal and infant complications of prenatal diagnosis of genital tract deformity were significantly lower than that of labor and postpartum diagnosis (P <0.05). Early diagnosis of genital tract deformity is the key to reduce maternal and child complications, and summarizes the main points of early diagnosis. It highlights the importance of genetic testing of genital abnormalities.