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目的探讨肿瘤相关物质(TSGF)在肿瘤诊断中的临床应用价值。方法用化学比色法测定对照组115例非肿瘤体检者,75例已明确诊断的肿瘤患者,21例肿瘤术后患者和29例随访肿瘤患者的TSGF的血清水平。结果TSGF的均值分别为(53.9±6.5)U/mL,(73.6±9.1)U/mL,(59.4±6.8)U/mL和(55.7±7.2)U/mL,患者与对照组比,差异均有统计学意义(P<0.05),TSGF的检出率分别为3.5%,79.4%,19.0%和10.3%,诊断效率为84.2%。结论TSGF测定对肿瘤的诊断有较高的灵敏度和特异性,在肿瘤的早期诊断、疗效观察和监测肿瘤复发和转移有较大的临床应用价值,可提高对肿瘤的早期诊断率。
Objective To investigate the clinical value of tumor related substances (TSGF) in the diagnosis of tumors. Methods The serum levels of TSGF in control group of 115 non-tumor subjects, 75 patients with definite diagnosis, 21 patients with postoperative tumor and 29 patients with follow-up were measured by chemical colorimetry. Results The average values of TSGF were (53.9 ± 6.5) U / mL, (73.6 ± 9.1) U / mL, (59.4 ± 6.8) U / mL and (55.7 ± 7.2) U / mL, (P <0.05). The detection rates of TSGF were 3.5%, 79.4%, 19.0% and 10.3%, respectively. The diagnostic efficiency was 84.2%. Conclusion TSGF has high sensitivity and specificity for the diagnosis of tumors. It has great clinical value in early diagnosis, observation of curative effect and monitoring of tumor recurrence and metastasis, which can improve the early diagnosis rate of tumor.