滋养细胞融合在胎盘结构的形成及维护胎儿正常发育方面起着重要作用,并且子痫前期、重复性流产等病理妊娠与滋养细胞融合异常有着密切关系。因此,深入研究滋养细胞融合机制对妊娠合并症的诊断、治疗及预防有着重要的意义,现就其相关进展作以综述。 Trophoblast fusion plays an important role in the formation of placenta and maintenance of the normal development of the fetus, and there is a close relationship between abnormal gestational pregnancy such as preeclampsia and recurrent miscarriage and trophoblastic abnormalities. Therefore, in-depth study of trophoblast fusion mechanism for the diagnosis, treatment and prevention of pregnancy complications is of great significance, are reviewed for their related progress.