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作者研究了34例迟发性皮肤卟啉症(简称PCT),其中男27(年龄为29~65岁);女7(年龄为28~65岁),都采用小剂量氯奎治疗,每周2次,每次125mg,共3~8月。治疗前后均进行全面的临床和实验室检查。18例是在其临床征象一出现就施行肝组织穿刺活检,而对没治疗过或曾用放血术的16例是在1~12月内完成。于活检后2周内开始氯奎治疗。治疗结束后,23例在开始2个月内,10例在第1年内,1例在2年后进
The authors studied 34 cases of delayed-onset skin porphyria (PCT), of which 27 male (aged 29 to 65 years) and 7 female (aged 28 to 65 years), were treated with low-dose chlor- 2 times, each 125mg, a total of 3 to August. Before and after treatment were comprehensive clinical and laboratory tests. Twenty-eight patients underwent liver biopsy on the appearance of their clinical signs, while 16 of the untreated or previously bleeding patients were completed within 1-12 months. Clonidine was started within 2 weeks after biopsy. At the end of treatment, 23 patients were within 2 months of onset, 10 were in year 1, and 1 was 2 years later