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目的观察鼠神经生长因子治疗小儿脑性疾病的临床疗效。方法将40例新生儿重症监护室住院患儿随机分为治疗组和对照组各20例。2组患儿均采用脑电治疗、捏脊及肢体康复功能训练,中药薰洗治疗、水疗、电针治疗,冷热敷等基础治疗,对照组另给予脑蛋白水解物注射液,治疗组另给予鼠神经生长因子。治疗后,比较2组临床疗效和不良反应。结果治疗组总有效率为85.0%高于对照组的75.0%,差异有统计学意义(P<0.05)。2组均未出现不良反应。结论注射用鼠神经生长因子对小儿脑性疾病的治疗效果明显,值得推广应用。
Objective To observe the clinical efficacy of murine nerve growth factor in the treatment of cerebral diseases in children. Methods Forty neonates with intensive care unit admitted to hospital were randomly divided into treatment group (n = 20) and control group (n = 20). Two groups of children were treated with electroencephalography, chiropractic and limb rehabilitation training, traditional Chinese medicine Kaoru treatment, hydrotherapy, electro-acupuncture, hot and cold and other basic treatment, the control group was given another brain protein hydrolyzate injection, the treatment group GDNF was given to rats. After treatment, the clinical efficacy and adverse reactions in the two groups were compared. Results The total effective rate was 85.0% in the treatment group, which was significantly higher than that in the control group (75.0%, P <0.05). No adverse reactions occurred in both groups. Conclusion The injection of rat nerve growth factor in children with cerebral disease treatment effect is obvious, it is worth promoting.