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流行病学模式显示枯氏锥虫的传播最初仅限于热带森林中特殊的生活史过程。在那里锥蝽以南美大陆幅员广阔地区的小型哺乳动物为吸血对象,而没有人类参与锥虫病的自然循环。枯氏锥虫的存在对锥蝽及已自然感染的哺乳动物似乎并无重要影响,提示长期的适应使不同种生物之间达到了平衡。枯氏锥虫经媒介的传播只限于新大陆,而锥蝽的分布遍及美洲各地。
Epidemiological patterns show that the transmission of Trypanosoma cruzi was initially limited to a special life history process in tropical forests. There, Labiatae is a vampire mammal in a large area of South American continent without any human involvement in the natural circulation of trypanosomiasis. The presence of Trypanosoma cruzi does not appear to have a significant effect on both T. aurata and naturally infected mammals, suggesting that long-term adaptation may strike a balance between different species of organisms. Trypanosoma brucei spread through the media is limited to the New World, while the stink bug spreads throughout the Americas.