Kupffer相关论文
Kupffer细胞是肝脏中所占比例最高的免疫细胞,它可以作为抗原呈递细胞参与肿瘤监测以及肝脏的再生过程,在先天免疫反应和宿主防御......
目的:建立流式细胞仪分选小鼠肝脏Kupffer细胞(KCs)的方法.方法:小鼠肝脏经胶原酶灌注后密度梯度离心法分离非实质细胞,流式细胞分......
目的明确中性粒细胞弹性蛋白酶抑制剂Sivelestat对非酒精性脂肪性肝炎(nonalcoholic steatohepatitis,NASH)的防治作用及可能机制......
非酒精性脂肪性肝病(NAFLD)是与胰岛素抵抗和遗传易感因素相关的代谢性肝脏损伤疾病,疾病谱包括非酒精性单纯性脂肪肝(NAFL)、非酒......
Liver cirrhosis is the final pathological result of various chronic liver diseases,and fibrosis is the precursor of cirr......
Platelets contain bio-physiological substances, including insulin-like growth factor-1, vascular endothelial growth fact......
Noninvasive diagnoses of nonalcoholic fatty-liver disease(NAFLD) involve the use of serologic markers and imaging method......
Superparamagnetic iron oxide-enhanced magnetic resonance imaging for focal hepatic lesions: Systemat
AIM: To evaluate the performance of superpara-magnetic iron oxide(SPIO)-enhanced magnetic resonance imaging(MRI) in the ......
Kupffer cells play a central role in the pathogenesis of alcoholic hepatitis(AH). It is believed that alcohol increases ......
Elevated iron stores as indicated by hyperferritinemiawith normal or mildly elevated transferrin saturation a n d m o s ......
Matrix metalloproteinases(MMPs) are a family ofproteases using zinc-dependent catalysis to break down extracellular matr......
目的探索慢性乙型肝炎病毒(HBV)感染树鼩Kupffer细胞Toll样受体(TLR)家族中的TLR2和TLR4在mRNA水平的表达情况及其对Kupffer细胞功......
目的 :探讨肝脏Kupffer细胞 (KC)在脾内途径的肝脏靶向性基因治疗中的抗原提呈作用及可能机制。方法 :以结肠癌肝转移小鼠为模型 ,......
一、肝脏在免疫中所起的作用 肝脏含有丰富的吞噬细胞(Kupffer细胞),具有滤过和清除来自肠道各种抗原(微生物、毒素和食物蛋白等)......
脂质体呈微小球形,由单一或更多的同心磷脂质组成,静脉注射后即被肝脏主要是 Kupffer 氏细胞、骨髓及脾内的巨噬细胞、类网状内皮......
众所周知 ,在酒精性肝损害的发病和进展上存在着性别差异 ,在饮用同量的情况下 ,女性较之男性却发生严重的肝损害。此种现象业经经......
目的研究超顺磁性氧化铁纳米粒(SPIO)作为MRI对比剂在肝硬化肝癌组织中分布变化情况,探讨其用于分子靶向成像的可行性。方法 SPF级......
AIM:To observe the effects of Kupffer cells on hepaticdrug metabolic enzymes.METHODS:Kunming mice were ip injected with......
Iron overload and cofactors with special reference to alcohol,hepatitis C virus infection and steato
There are several cofactors which affect body iron metabolism and accelerate iron overload.Alcohol and hepatic viral inf......
Obesity is increasingly being recognized as a risk factor for a number of benign and malignant gastrointestinal conditio......
Naofen promotes TNF-α-mediated apoptosis of hepatocytes by activating caspase-3 in lipopolysaccharid
AIM:To investigate whether naofen is involved in tumor necrosis factor(TNF)-α-mediated apoptosis of hepatocytes induced......
Excessive ethanol consumption affects virtually any organ,both by indirect and direct mechanisms.Considerable research i......
AIM:To clarify the location and distribution of Kupffer cellsin hepatocellular carcinoma(HCC),and to investigate theirr......
病人,男,60岁.因健康体检发现肝脏占位性病变2周于2002年11月11日入院.病人既往体健,无烟酒嗜好,无肝炎病史,无外伤、手术及有毒物......
INTRODUCTION Our previous study has proved that Kupffer cellsmay have an inhibitory effect on the process ofhepatocarci......
对单纯用二乙基亚硝胺 (DENA)及氯化钆 (GC)或酵母多糖 (ZM)分别阻断或激活 Kupffer细胞后 ,同时给以 DENA所引起的大鼠肝癌中的增......
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Superparamagnetic iron oxide (SPIO) nanoparticles are effective contrast agents for enhancement of magnetic resonance im......
目的:探讨糖皮质激素诱导的肿瘤坏死因子相关蛋白配体(GITRL)在脂多糖(LPS)诱导的Kupffer细胞(KCs)凋亡中的作用。方法:分离BALB/c......
Neutrophil depletion-but not prevention of Kupffer cell activation-decreases the severity of cerulei
AIM:To determine whether neutrophil depletion andKupffer cell inhibition might combine their protectiveeffects to decre......
在希腊,有大量抗-HBe 阳性而无活跃病毒复制证据的晚期肝病病人。目前对治疗慢性活动性乙型肝炎(CAHB)仍是一个难题。为了治疗这......
AIM: To examine the effects of adiponectin on the functions of Kupffer cells, key modulators of lipopolysaccha-ride (LPS......
BACKGROUND:With the development of hepatic surgery especially liver transplantation,the pathophysiological processes of ......
36岁,男性,十二指肠溃疡病者,过去无肝脏疾病,因溃疡出血应用Cimetidnie,每日400mg维持量治疗,75日中断治疗后发现肝炎。肝活检标......
内毒素血症已被认为是梗阻性黄疸患者术后发病和死亡的主要原因。革兰氏阴性细菌的毒素溶解产物是胆汁郁积者发生肝肾疾病、血液......
本文报告一例病程长达6个月的肠道传播的非甲非乙型肝炎[Enterically Transmitted non-A non-B Hepatitis,简称HNANB(E)]病人肝穿......
肝脏局灶性结节性增生(Focal Nod-ular Hyper plasia,简称 FNH)是肝脏少见的良性占位性病变。到目前为止,国内见诸报告的不多,在......
胆汁淤积是胆汁流障碍使正常数量的胆汁不能抵达十二指肠,伴有胆汁内成分如结合胆红素、胆汁酸、胆固醇及碱性磷酸酶(AKP)等反流......
肝脏非实质细胞参与了肝脏的大多数病理生理过程。它们还参加了炎症、血液及免疫紊乱、休克、脓毒血症等病理过程［１］。它们自身的数量......
本实验采用新西兰大耳白兔制作胆道阻塞模型。研究了胆道阻塞以后肝脏抗氧化酶系的变化。结果表明,胆总管结扎二周后肝组织谷胱甘......
为了解内毒素（LPS）/肿瘤坏死因子（TNF）所致肝细胞损害的机制，以乳酸脱氢酶（LDH）及噻唑蓝染色（MTT）为细胞毒性指标，利用Wistar大鼠肝细胞进行......
目的观察术前抗内毒素治疗对阻塞性黄疸病人内毒素血症的抑制作用。方法阻塞性黄疸病人分三组在术前分别给予一般治疗(OJ组),口服......
ORIGlNALARTlCLEDynamicchangesoftype1,IIIandlVcollagensynthesisanddistributionofc0llagen-producingcellsincarbontetrachlor......
