大蒜作为药物应用,在我国已有悠久历史,它的有效成分是大蒜素。上海第二制药厂合成药研究所化学合成的大蒜新素,经气相色谱——质谱、核磁共振、红外光谱、元素分析测定,分子式、分学结构、杀菌、抑菌效价均与天然得到的大蒜素一致。近几年来作为中西医结合疗法被广泛应用于临床。但国内外文献未见用于治疗根尖病的报道。我们从1979年6月至1980年5月,用于瘘管型慢性根尖脓肿,作瘘管通过一次疗法,计156例,对其中102例进行随访观察,治愈率达95.09％。现将102例 Garlic as a drug application, has a long history in our country, its active ingredient is allicin. Allicin synthesized by Shanghai Institute of Synthetic Medicine, No.2 Pharmaceutical Factory of Shanghai No.2 Pharmaceutical Factory was confirmed by gas chromatography-mass spectrometry, nuclear magnetic resonance, infrared spectroscopy, elemental analysis, molecular formula, molecular structure, bactericidal and antibacterial activity Allicin consistent. In recent years as an integrated Chinese and Western medicine therapy is widely used in clinical. However, no literature has been reported for the treatment of root tip disease at home and abroad. We used from June 1979 to May 1980 for fistula chronic apical abscess, fistula through a therapy, including 156 cases, of which 102 cases were followed up, the cure rate was 95.09%. Now 102 cases