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目的研究埃必定的抗炎作用，为埃必定应用于临床提供理论基础。方法应用鼠耳肿胀、角叉菜胶足肿胀、佐剂性关节炎、角叉菜胶气囊模型观察埃必定的抗炎作用，用酵母致热模型观察埃必定的解热作用并对胃肠道溃疡形成进行观察。结果埃必定对鼠耳肿胀、角叉菜胶足肿胀和佐剂性关节炎均有明显抑制作用。对炎症性渗出、白细胞游走和毛细血管通透性增高均有明显抑制作用。对酵母引起的体温升高有退热作用。胃肠道粘膜毒性较吲哚美辛低。结论埃必定具有抗炎、解热作用，此作用与吲哚美辛相似，但对胃肠道粘膜溃疡形成作用却远低于吲哚美辛。
Objective To study the anti-inflammation effect of erbitine and provide a theoretical basis for the application of erbitine in clinical practice. Methods The ear swelling, carrageenan foot swelling, adjuvant arthritis, and carrageenan balloon model were used to observe the anti-inflammatory effect of erbitine. The yeast fever model was used to observe the antipyretic effect of erbidine and the gastrointestinal tract. Ulcer formation was observed. The results showed that iridine inhibited ear swelling, carrageenan foot swelling and adjuvant arthritis. Inflammatory exudation, leukocyte migration and increased capillary permeability were all significantly inhibited. There is an antipyretic effect on elevated body temperature caused by yeast. Gastrointestinal mucosal toxicity is lower than indomethacin. Conclusion Erbitamine has anti-inflammatory and antipyretic effects. This effect is similar to that of indomethacin, but it is far less effective than indomethacin in the formation of gastrointestinal mucosal ulcers.