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目的观察老年女性冠心病患者冠状动脉特点及相关的临床危险因素。方法入选年龄在≥70岁女性冠心病患者135例作为观察组,平均(75.6±8.6)岁,同时入选老年男性及<70岁女性冠心病患者135例作为对照组,所有患者均行常规生化、心电图、超声心动图以及冠状动脉造影检查。结果老年女性有糖尿病史,患非ST段抬高心肌梗死者明显多于老年男性,而吸烟少于男性;老年女性患者CRP水平明显高于男性,LDL-C水平低于男性LVEF低于男性(P<0.05);老年女性双支病变,B2型病变及C型病变比例增多(P<0.05)。同<70岁女性相比,老年女性糖尿病史,患ST段抬高心肌梗死比例明显增高;LVEF减低(P<0.05);C型病变与慢性完全闭塞病变明显增多,而单支病变较少(P<0.05)。结论老年女性冠心病患者临床风险较高。
Objective To observe the characteristics of coronary artery in elderly women with coronary heart disease and related clinical risk factors. Methods One hundred and seventy-five-year-old women with coronary heart disease were enrolled as the observation group, with an average of (75.6 ± 8.6) years old. 135 elderly patients and <70 years old women with coronary heart disease were enrolled as control group. All patients underwent routine biochemical, ECG, echocardiography and coronary angiography. Results The elderly women had a history of diabetes mellitus, and those with non-ST-elevation myocardial infarction were significantly more than the elderly men and smoked less than men. The elderly women had significantly higher CRP levels and lower LDL-C levels than those with male LVEFs P <0.05). The proportion of elderly patients with double-vessel disease, type B2 disease and type C disease increased (P <0.05). Compared with 70-year-old women, the elderly women with diabetes mellitus had a significantly higher proportion of patients with ST-elevation myocardial infarction, LVEF (P <0.05), C-type lesions and chronic total occlusion lesions were significantly increased, P <0.05). Conclusion The elderly patients with coronary heart disease clinical risk is higher.